Remark 18.2.8. In Definition 18.2.1, the system $\sigma$ can be chosen based on the bornology of $E$, and the definition of small-ness depends exclusively on $\sigma$. As such, there is an apparent disconnect between differentiation and the topology of the domain.
Consider for example a Hilbert space equipped with its norm and weak topology. The norm itself is differentiable with respect to both topologies, because the bounded sets coincide. Moreover, the data for differentiability needs to only come from a neighbourhood of $0$ in the norm topology. As such, a function may be differentiable even if its domain is too small to have an interior.
A method of extending this sense of differentiability is to require that every extension of the function to some open set, or to the entire space is differentiable. Given that this paves way to confusion for related definitions of differentiability, this definition is not formally included here.